Abstract: The paper is about the cyclization reaction of dichloropropanol preparing epoxy chloropropane in a micro-channel reactor. The influence of reaction temperature，the ratio of two materials，thedetention time on the yield of epoxy chloropropane are studied. The optimal parameters for reaction process are obtained as 50 ℃ reaction temperature，1∶1.2 for the ratio of dichloropropanol and NaOH，45 s detention time，20% weight concentration of sodium hydroxide solution，under which the yield of the epoxy chloropropane can reach up to 95.2%. The STC in micro-channel reactor is more than 100 times of that in a regular reactor. Comparing with traditional technological process，this new micro-channel reaction process makes the yield of epoxy chloropropane increased by 10% with less energy consumption，and the waste water discharge reduced by 45%.

Key words: dichloropropanol, cyclization reaction, epichlorohydrin, micro-channel reactor

摘要： 研究了微通道反应器内二氯丙醇的环化制备环氧氯丙烷的反应，考察了反应温度、原料配比、停留时间等单因素对环氧氯丙烷收率的影响。实验确定了较优的工艺参数组合：环化反应温度50 ℃，二氯丙醇与氢氧化钠的摩尔比1∶1.2，停留时间45 s，NaOH质量分数20%时ECH的收率达到95.2%。在微通道反应的时空转化率要比常规反应高出两个数量级。与传统的工艺方法相比，微通道反应中环氧氯丙烷的收率提高了10%，降低了过程的能耗，废水排放量减少了45%。

关键词: 二氯丙醇, 环化反应, 环氧氯丙烷, 微通道反应器